Spectral karyotyping of metaphases
Roth Lab
Understanding DNA double-strand break repair and chromosomal translocations through V(D)J recombination
The David B. Roth Lab studies the interface between V(D)J recombination and DNA repair, with a particular interest in the functions of the RAG proteins.
Research Keywords: RAG Proteins | nonhomologous end joining and alternative NHEJ | regulatory controls to prevent transposition and errors in joining
Postdoctoral position in the Roth Lab
We are recruiting a postdoctoral fellow to pursue research in genomic stability mechanisms Read more
Roth Lab is on the Move
The Roth Lab has relocated to MSB 507 Read more
The Roth Lab Publishes in Molecular Cell
We show that a multifaceted DNA damage signaling/repair complex, the MRE11 complex, plays a critical role in promoting proper joining of V(D)J recombination intermediates during lymphocyte differentiation Read more